Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients

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Mar 27, 2025 (publication date) through Apr 1, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Hepatol. Mar 27, 2025; 17(3): 103261
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.103261

Table 1 Univariate and multivariate Cox regression analyses for recurrent variceal bleeding before and after propensity score matching

Characteristics	Before PSM, univariate analyses (n = 815)			Before PSM, multivariate analyses (n = 815)			After PSM, univariate analyses (n = 662)			After PSM, univariate analyses (n = 662)
Characteristics	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P
Group B	0.546	0.366-0.815	0.003^b	0.623	0.387-1.004	0.052	0.520	0.330-0.818	0.005^b	0.520	0.330-0.818	0.005^b
Kalium	0.305	0.120-0.774	0.012^a	0.305	0.119-0.783	0.014^a
Cancer antigen 153	0.691	0.493-0.968	0.032^a	0.713	0.500-1.016	0.061
Creatinine	1.952	1.123-3.394	0.018^a	1.679	0.943-2.990	0.078
Pre-TIPS inferior vena cava pressure	1.629	1.010-2.628	0.046^a	1.556	0.950-2.547	0.079
Pre-TIPS Child-Turcotte-Pugh score	2.513	1.095-5.766	0.030^a	1.983	0.841-4.679	0.118
Portal vein diameter	2.487	1.216-5.084	0.013^a	1.279	0.548-2.984	0.569
Alkaline phosphatase	0.680	0.460-1.006	0.054
Alanine aminotransferase	0.774	0.563-1.065	0.116

^aP < 0.05.

^bP < 0.01.

HR: hazard ratio; PSM: Propensity score matching; TIPS: Transjugular intrahepatic portosystemic shunt.

Citation: Wang ZB, Zhu B, Meng MM, Wu YF, Zhang Y, Li DZ, Tian H, Wang FC, Lv YF, Ye QX, Liu FQ. Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients. World J Hepatol 2025; 17(3): 103261
URL: https://www.wjgnet.com/1948-5182/full/v17/i3/103261.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i3.103261