Metabolic dysfunction-associated steatotic liver disease and omega-6 polyunsaturated fatty acids: Friends or foes

doi:10.4254/wjh.v17.i3.102286

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Mar 27, 2025; 17(3): 102286
Published online Mar 27, 2025. doi: 10.4254/wjh.v17.i3.102286

Table 1 Biochemical structure of omega-6 subtypes

Omega family	Common name	Systematic name	Abbreviations
n-6	LA	all-cis-9,12-octadecadienoic acid	18:2n-6 or 18:2
	GLA	all-cis-6,9,12-octadecatrienoic acid	18:3n-6 or 18:3
	DGLA	all-cis-8,11,14-eicosatrienoic acid	20:3n-6 or 20:3
	AA	all-cis-5,8,11,14-eicosatetraenoic acid	20:4n-6 or 20:4
	DTA	all-cis-7,10,13,16-docosatetraenoic acid	22:4n-6 or 22:4
	Tetracosatetraenoic acid (TTA _n-6)	all-cis-9,12,13 ,5,18-tetracosatetraenoic acid	24:4n-6 or 24:4
	Tetracosapentaenoic acid (TPA _n-6)	all-cis-6,9,12,15,18-tetracosapentaenoic acid	24:5n-6 or 24:6
	DPA _n-6	all-cis-4,7,10,13,16-docosapentaenoic acid	22:5n-6 or 22:5

LA: Linoleic acid; GLA: Gamma-linolenic acid; DGLA: Dihomo-gamma-linolenic acid; AA: Arachidonic acid; TTA _n-6: Tetracosatetraenoic acid; TPA _n-6: Tetracosapentaenoic acid; DPA _n-6: Docosapentaenoic acid.

Citation: Hegazy MA, Ahmed SM, Sultan SM, Afifi OF, Mohamed MA, Azab AE, Hassanen MA, Zaben RK. Metabolic dysfunction-associated steatotic liver disease and omega-6 polyunsaturated fatty acids: Friends or foes. World J Hepatol 2025; 17(3): 102286
URL: https://www.wjgnet.com/1948-5182/full/v17/i3/102286.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i3.102286