Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling

Figure 4 Effect of Yinchenhao decoction on constitutive androstane receptor expression and its nuclear heterotopy in liver and kidney tissues of rats with obstructive jaundice. A: Immunohistochemical results of constitutive androstane receptor (CAR) in liver tissues of rats with obstructive jaundice (OJ); B: The average optical density of CAR protein in liver cells; C: Immunohistochemical results of CAR in kidney tissues of rats with OJ; D: The average optical density of CAR protein in renal tubular epithelial cells; E: The expression rate of CAR protein in hepatocyte nuclei; F: CAR protein expression rate in renal tubular epithelial cell nuclei. ^aP < 0.05 vs Sham (group S); ^bP < 0.01 vs group S; ^cP < 0.05 vs OJ model (group O); ^dP < 0.01 vs group O; AOD: Average optical density; Group O: Obstructive jaundice model; group S: Sham; Y Group: Yinchenhao decoction-treated.