Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling

Figure 3 Effect of Yinchenhao decoction on bile acid active transporters in rats with obstructive jaundice. A and B: Levels of expression of the cytochrome P450 family 3 subfamily A member 4 (P4503A4), UDP glucuronosyltransferase family 1 member A1 (UGT1A1), multidrug resistance-associated protein (MRP) 3, and 4 in the liver tissue; C and D: Multidrug resistance-associated protein (MRP) 2, and 4 in the kidney tissues; and levels of expression of MRP 2, 4 in the renal tissue. ^aP < 0.05 vs group S; ^bP < 0.01 vs Sham (group S); ^cP < 0.05 vs OJ model (group O); ^dP < 0.01 vs group O. Group O: Obstructive jaundice model; Group S: Sham; Y group: Yinchenhao decoction-treated.