Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling

Figure 2 Impact of Yinchenhao decoction on bilirubin, liver function, urine output, and liver cell histology in rats with obstructive jaundice. A and B: Development of obstructive jaundice (OJ) rat models; C-F: Bilirubin (C), liver function (D), bile acid (E), and urine output (F) in rats with OJ. ^aP < 0.05 vs group S; ^bP < 0.01 vs group S; ^cP < 0.05 vs group O; ^dP < 0.01 vs group O; G: Histological alterations in liver and kidney tissues of rats with OJ. Group O: Obstructive jaundice model; group S: Sham; Y Group: Yinchenhao decoction-treated; TSBA: Total serum bile acid; DBIL: Direct bilirubin; TBIL: Total bilirubin; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase; Clr: Renal clearance; TUBA: Total urinary bile acid.