Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling

Figure 1 Screening and network pharmacology analysis of Yinchenhao decoction blood components and obstructive jaundice targets. A: Study workflow: Yinchenhao decoction administered after obstructive jaundice for 3 days, followed by sacrifice and tissue collection on day 10; B: Venn diagrams illustrating the Yinchenhao decoction (YCHD) blood components and potential targets for obstructive jaundice; C: Protein-protein interaction network with 65 nodes and 382 edges; D: The top 10 terms for biological process, molecular function, and cellular component in Gene Ontology functional annotations; E: Kyoto Encyclopedia of Genes and Genomes enrichment analysis of key targets in YCHD; F: Network diagram illustrating the relationship between YCHD components, targets, and pathways, with 175 nodes: 11 components (orange hexagons), 144 targets (pink hexagons), and 20 pathways (green circles), connected by 957 edges. YCHD: Yinchenhao decoction; GO: Gene Ontology; EGFR: Epidermal growth factor receptor.