Dysregulation of bile acid signal transduction causes neurological dysfunction in cirrhosis rats

Figure 1 Thioacetamide-induced bile acid feeding in cirrhotic rats led to increased anxiety-like behavior (mean ± SD, n = 10). A-D: The total distance of the open-field experiment, the number of central areas of the open open-field experiment, and the open arm of the elevated cross-experiment, percentage of entry times and percentage of residence time of open arm in elevated cross test. ^aP < 0.05 compared with vehicle + control diet group; ^bP < 0.05 compared with thioacetamide group. TAA: Thioacetamide.