Hepatitis B virus confers innate immunity evasion through hepatitis B virus-miR-3 down-regulation of cGAS-Sting-IFN signaling

Figure 1 CGAS protein expression in presence of hepatitis B virus. A: CGAS protein expression in HepG2.2.15 cells vs HepG2 cells; B: CGAS mRNA levels in HepG2.2.15 cells vs HepG2 cells; C: CGAS protein expression in HepG2-NTCP cells treated with hepatitis B virus (HBV) from HepG2.2.15 cells supernatant after 72 hours; D: CGAS mRNA levels in HepG2-NTCP cells treated with HBV from HepG2.2.15 cells supernatant after 72 hours; E: CGAS protein expression in HepG2 cells transfected with different doses of pHBV1.3; F: CGAS mRNA levels in HepG2 cells transfected with different doses of pHBV1.3. Each experiment was repeated three times. Data are presented as mean ± SD.