Clinical characteristics of patients with hepatitis and cirrhosis and the construction of a prediction model

Table 1 Comparison of baseline data between modeling and verification cohorts, mean ± SD/n (%)

Index		Total cases (n = 1070)	Modeling queue (n = 749)	Verification queue (n = 321)	t/χ2/Z	P value
Gender	Man	679 (63.46)	487 (65.02)	192 (59.81)	2.627	0.105
	Woman	391 (36.54)	262 (34.98)	129 (40.19)
Age (years)		46.84 ± 11.73	46.58 ± 11.77	47.45 ± 11.63	1.112	0.266
Hepatitis classification	Mild	242 (22.62)	161 (21.50)	81 (25.23)	0.849	0.396
	Moderate	753 (70.37)	538 (71.83)	215 (66.98)
	Serious	75 (7.01)	50 (6.68)	25 (7.79)
Alb (× 109/L)		43.11 ± 4.70	43.02 ± 4.65	43.32 ± 4.79	0.958	0.338
LDH (U/L)		210.73 ± 93.70	210.07 ± 73.36	212.28 ± 129.41	0.353	0.724
CHE (U/L)		7376.59 ± 2247.89	7298.93 ± 2190.67	7557.79 ± 2369.69	1.728	0.084
WBC (× 109/L)		5.19 ± 1.53	5.19 ± 1.51	5.20 ± 1.59	0.098	0.922
RBC (× 1012/L)		4.74 ± 0.50	4.73 ± 0.51	4.74 ± 0.49	0.297	0.766
HGB (g/L)		145.45 ± 16.13	145.56 ± 15.96	145.22 ± 16.54	0.316	0.752
ANC (× 109/L)		2.84 ± 16.13	2.81 ± 1.07	2.89 ± 1.25	1.064	0.288
ALC (× 109/L)		1.86 ± 0.65	1.88 ± 0.66	1.84 ± 0.64	0.917	0.360
GOT/GPT		0.76 ± 0.43	0.75 ± 0.42	0.78 ± 0.46	1.040	0.299
PTA (%)		109.50 ± 18.79	108.16 ± 40.22	112.61 ± 40.40	1.545	0.123
HBeAg (S/CO)		1745.74 ± 32177.8	2355.23 ± 38449.88	323.60 ± 526.52	0.946	0.344
INR		1.02 ± 0.12	1.03 ± 0.31	1.00 ± 0.31	1.451	0.147
PT (second)		11.76 ± 1.39	11.84 ± 4.38	11.57 ± 3.38	0.986	0.325
HA (ng/mL)		141.29 ± 142.55	147.90 ± 173.41	125.87 ± 160.61	1.946	0.052
LN (μg/L)		54.47 ± 42.36	56.44 ± 55.54	49.87 ± 43.43	1.886	0.060
PLT (× 109/L)		362.35 ± 4394.84	439.84 ± 5251.83	181.54 ± 63.11	0.881	0.379

Alb: Albumin; LDH: Lactate dehydrogenase; CHE: Cholinesterase; WBC: White blood cell; RBC: Red blood cell; HGB: Hemoglobin; ANC: Absolute neutrophil count; ALC: Absolute lymphocyte count; PTA: Prothrombin activity; GOT: Aspartate aminotransferase; GPT: Alanine aminotransferase; HBeAg: Hepatitis B E antigen; INR: International normalized ratio; PT: Plasma prothrombin time; HA: Hyaluronic acid; LN: Laminin; PLT: Platelet count.