Modern ultrasound techniques for diagnosing liver steatosis and fibrosis: A systematic review with a focus on biopsy comparison

Table 4 Point-shear wave elastography diagnostic efficacy (area under the receiver operating characteristic curves for fibrosis detection)

Ref.	Number of patients	Disease/diagnose	Diagnostic method	Fibrosis stage	AUROC (CI)	Assessment
Lee et al[31]	87	CLD	p-SWE	≥ F2	0.872 (0.777-0.937)	Good
				F4	0.886 (0.794-0.947)	Good
Fang et al[25]	121	CLD	p-SWE	≥ F2	0.855 (0.778-0.932)	Good
				≥ F3	0.890 (0.826-0.954)	Good
Saadi et al[41]	216	CLD	p-SWE	F0-F1	0.744 (0.67-0.82)	Acceptable
				F3	0.82 (0.74-0.89)	Good
				F4	0.95 (0.91-0.98)	Acceptable
Atzori et al[22]	160	CLD	p-SWE - Philips ElastPQ	F0/1	0.828 (0.762-0.895)	Good
				F3/4	0.812 (0.734-0.889)	Good
				F4	0.856 (0.753-0.938)	Good
Atzori et al[22]	160	CLD	p-SWE - Siemens VTQ	F0/1	0.741 (0.659-0.823)	Acceptable
				F3/4	0.782 (0.702-0.861)	Acceptable
				F4	0.826 (0.734-0.918)	Good
Roccarina et al[40]	671	NAFLD	p-SWE by ElastPQ	F > 1	0.835 (0.72-0.93)	Good
				F > 2	0.831 (0.78-0.90)	Good
				F > 3	0.864 (0.82-0.93)	Good
				F = 4	0.952 (0.92-0.99)	Excellent
Garcovich et al[26]	253	CLD	X + p-SWE	F ≥ 2	0.96 (0.93-0.99)	Excellent
				F ≥ 3	0.98 (0.97-1.00)	Excellent
				F4	0.99 (0.98-1.00)	Excellent

AUROC: Area under the receiver operating characteristic curve; CLD: Chronic liver disease; p-SWE: Point-shear wave elastography; VTQ: Virtual Touch^TM Quantification.