Impact of liver cirrhosis on morbidity and mortality of patients admitted to the hospital with necrotizing fasciitis

Table 1 Baseline demographic and clinical characteristics, n (%)

Characteristics	Without cirrhosis	With cirrhosis	P value
Total	14605 (98)	315 (2)
Female	6718 (85)	104 (15)	0.03
Mean age, years	52.7	52.3
Charlson comorbidity index score			< 0.01
0	3651 (25)	0 (0)
1	3943 (27)	69 (22)
2	2774 (19)	66 (21)
≥ 3	4235 (29)	179 (57)
Insurance type			0.73
Medicare	4673 (32)	94 (30)
Medicaid	4527 (31)	116 (37)
Private insurance	3943 (27)	81 (26)
Self-pay	1460 (10)	22 (7)
Comorbidities
Sepsis	2190 (15)	69 (22)	0.14
Diabetes mellitus	8032 (40)	126 (55)	0.015
Hypertension	8470 (58)	176 (56)	0.67
Obesity	5257 (36)	110 (35)	0.88
Chronic kidney disease	1898 (13)	78 (25)	< 0.01
Alcohol use disorder	438 (3)	75 (24)	< 0.01
Chronic obstructive pulmonary disease	1460 (10)	53 (17)	0.5
Chronic heart failure	730 (5)	9 (3)	0.45
Coronary artery disease	1898 (13)	40 (13)	0.38
Gastroesophageal reflux disease	1898 (13)	53 (17)	0.38
Cigarette smoking	4089 (28)	113 (36)	0.13