C23 ameliorates carbon tetrachloride-induced liver fibrosis in mice

Figure 3 C23 inhibited the activation of hepatic stellate cells induced by carbon tetrachloride. A: The generation and localization of collagen I in the liver were analyzed using immunohistochemistry (IHC); B: The generation and localization of α-smooth muscle actin (α-SMA) in the liver were analyzed using IHC; C: The expression ratio of collagen I in each group was determined with image-pro plus (IPP); D: The expression ratio of α-SMA in each group was determined with IPP. ^aP < 0.05, ^bP < 0.01 vs carbon tetrachloride. CCl4: Carbon tetrachloride; α-SMA: α-smooth muscle actin.