Causal association between 731 immunocyte phenotypes and liver cirrhosis: A bidirectional two-sample mendelian randomization analysis

Figure 1 Diagram of this bidirectional mendelian randomization study design. The arrows indicate bidirectional causal relationships between liver cirrhosis and immunocyte phenotypes, and the causal pathway is blocked if a “fork” is placed in the arrowed line. IVW: Inverse variance weighting; MR: Mendelian randomization; SNPs: Single-nucleotide polymorphisms; IVs: Instrumental variables.