Causal association between 731 immunocyte phenotypes and liver cirrhosis: A bidirectional two-sample mendelian randomization analysis

Table 4 Reverse mendelian randomization sensitivity analysis

Outcome panel	Outcome traits	Inverse variance weighted		MR-Egger
		Q value	P value	intercept	P value
B cell	IgD+ CD38 bright AC	35.51	0.224	-0.014	0.401
B cell	IgD+ CD38 dim AC	30.73	0.429	-0.030	0.068
B cell	IgD+ AC	33.15	0.316	-0.028	0.094
B cell	Naive-mature B cell AC	27.47	0.599	-0.022	0.160
B cell	IgD+ CD24- AC	29.82	0.475	-0.019	0.250
cDC	CD62L- plasmacytoid DC AC	29.39	0.497	0.029	0.075
Myeloid cell	Im MDSC AC	29.23	0.506	0.019	0.249
Myeloid cell	Im MDSC% CD33 dim HLA DR- CD66b-	24.09	0.768	0.009	0.568
Myeloid cell	CD33- HLA DR+ AC	30.39	0.446	-0.004	0.790
TBNK	CD4+% leukocyte	16.12	0.982	0.007	0.670
TBNK	CD3- lymphocyte% leukocyte	17.10	0.971	0.013	0.443
Treg	CD28+ CD45RA- CD8 dim AC	37.39	0.166	0.000	0.997
B cell	CD20 on CD24+ CD27+	22.52	0.834	0.026	0.231
B cell	CD20 on sw mem	32.59	0.341	0.020	0.381
TBNK	FSC-A on B cell	25.61	0.695	0.017	0.345
Monocyte	CX3CR1 on monocyte	39.69	0.111	0.002	0.891
Monocyte	CX3CR1 on CD14- CD16+ monocyte	19.80	0.922	0.008	0.641
TBNK	SSC-A on B cell	32.70	0.336	-0.003	0.844
Treg	CD8 on CD28- CD8 bright	37.59	0.106	-0.003	0.877

TBNK: T cells, B cells, and natural killer cells; DC: Dendritic cells; AC: Absolute count; FSC-A: Forward scatter-A; SSC-A: Side scatter-A; CD: Cluster of differentiation.