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©The Author(s) 2024.
World J Hepatol. Aug 27, 2024; 16(8): 1131-1144
Published online Aug 27, 2024. doi: 10.4254/wjh.v16.i8.1131
Published online Aug 27, 2024. doi: 10.4254/wjh.v16.i8.1131
Table 2 Clinical pathological features of hepatocellular carcinoma according to tissue inhibitor of metalloproteinase-3 expression
Variable | LTE | n | HTE | |||
n | Percentage (%) | Percentage (%) | P value | |||
Total | 89 | 100.0 | 93 | 100.0 | ||
Age (years) | 0.78 | |||||
< 49 | 47 | 52.8 | 51 | 54.8 | ||
≥ 49 | 42 | 47.2 | 42 | 45.2 | ||
Gender | 0.18 | |||||
Male | 70 | 78.7 | 65 | 69.9 | ||
Female | 19 | 21.3 | 28 | 30.1 | ||
Race | 0.89 | |||||
Han | 44 | 49.4 | 45 | 48.4 | ||
Others | 45 | 50.6 | 48 | 51.6 | ||
Smoking | 0.38 | |||||
No | 70 | 78.7 | 68 | 73.1 | ||
Yes | 19 | 21.3 | 25 | 26.9 | ||
Drinking | 0.50 | |||||
No | 68 | 76.4 | 67 | 72.0 | ||
Yes | 21 | 23.6 | 26 | 28.0 | ||
HBsAg | 0.13 | |||||
Negative | 26 | 29.2 | 37 | 39.8 | ||
Positive | 63 | 70.8 | 56 | 60.2 | ||
Anti-HCV | 0.47 | |||||
Negative | 71 | 79.8 | 78 | 83.9 | ||
Positive | 18 | 20.2 | 15 | 16.1 | ||
AFP | 4.66 × 10-13 | |||||
Negative | 8 | 9.0 | 56 | 60.2 | ||
Positive | 81 | 91.0 | 37 | 39.8 | ||
Tumor size | 2.54 × 10-4 | |||||
≤ 5 cm | 16 | 18.0 | 40 | 43.0 | ||
> 5 cm | 73 | 82.0 | 53 | 57.0 | ||
ES grade | 3.84 × 10-4 | |||||
Low | 34 | 38.2 | 60 | 64.5 | ||
High | 55 | 61.8 | 33 | 35.4 | ||
TNM stage | 1.18 × 10-4 | |||||
I | 6 | 6.7 | 24 | 25.8 | ||
II | 35 | 39.3 | 43 | 46.2 | ||
III | 48 | 53.9 | 26 | 28.0 | ||
Liver cirrhosis | 0.14 | |||||
No | 32 | 36.0 | 24 | 25.8 | ||
Yes | 57 | 64.0 | 69 | 74.2 | ||
MVD | 2.97 × 10-3 | |||||
Low | 34 | 38.2 | 56 | 60.2 | ||
High | 55 | 61.8 | 37 | 39.8 | ||
PVTT | 2.32 × 10-5 | |||||
Negative | 49 | 55.1 | 78 | 83.9 | ||
Positive | 40 | 44.9 | 15 | 16.1 | ||
MVI | 2.99 × 10-4 | |||||
Negative | 45 | 50.6 | 71 | 76.3 | ||
Positive | 44 | 49.4 | 22 | 23.7 |
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Citation: Liang QJ, Long QQ, Tian FQ, Su QY, Zhu XY, Long XD. Tissue inhibitor of metalloproteinase-3 expression affects clini
copathological features and prognosis of aflatoxin B1-related hepatocellular carcinoma. World J Hepatol 2024; 16(8): 1131-1144 - URL: https://www.wjgnet.com/1948-5182/full/v16/i8/1131.htm
- DOI: https://dx.doi.org/10.4254/wjh.v16.i8.1131