Improvement of hepatic fibrosis after tenofovir disoproxil fumarate switching to tenofovir alafenamide for three years

Figure 2 Improvement rates (%) of alanine aminotransferase and aspartate aminotransferase to < 35 (male)/25 (female) and < 30 (male)/19 (female), aspartate aminotransferase to platelet ratio index to < 0. 5 and fibrosis-4 to < 1.45 at baseline and after switching week 144. A and B: There was a great improvement rates of alanine aminotransferase and aspartate aminotransferase to normalization (A) and improvement rates of aspartate aminotransferase to platelet ratio index to < 0.5 and fibrosis-4 to < 1.45 (B) after tenofovir disoproxil fumarate switching to tenofovir alafenamide for 144 weeks, compared to baseline. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; FIB-4: Fibrosis-4; APRI: Aspartate aminotransferase to platelet ratio index.