Current concepts in the management of non-cirrhotic non-malignant portal vein thrombosis

Figure 2 Suggested management algorithm for recent non-cirrhotic non-malignant portal vein thrombosis. ¹Major risk factors include: Myeloproliferative neoplasms, antiphospholipid syndrome, paroxysmal nocturnal haemoglobinuria, homozygous or compound heterozygous factor V Leiden or prothrombin G20210A gene mutations, personal or first-degree familial history of unprovoked deep vein thrombosis. ²Consider measuring D-dimer. If D-dimer > 500 ng/mL at 1 month following anticoagulation discontinuation consider long-term anticoagulation. NCPVT: Non-cirrhotic non-malignant portal vein thrombosis.