Ornithine aspartate effects on bacterial composition and metabolic pathways in a rat model of steatotic liver disease

Table 1 General characteristics of the nutritional model of metabolic-dysfunction associated steatotic liver disease

Variables	Control	MASLD	LOLA	P value
Body weight (g)	180.9 ± 37.4a	325.1 ± 92.2c	310 ± 56.1c	< 0.001
Fresh liver weight (g)	17.2 ± 2.4a	30.8 ± 4.3c	27.3 ± 2.6c	< 0.001
Triglycerides (mg/dL)	20.52 ± 3.4a	94.51 ± 30.4c	90.94 ± 33.2c	< 0.001
Total cholesterol (mg/dL)	3.17 ± 1.9a	45.57 ± 8.4c	39.88 ± 13.8c	< 0.001
Total lipid accumulation (fluorecence/μg protein)	160.3 ± 32.2a	2921 ± 769.9c	2123 ± 576c	< 0.001

^aP < 0.05 is considered significant, different letters indicate a significant difference between groups.

^cP < 0.05 is considered significant, different letters indicate a significant difference between groups.

Variables expressed by mean ± SD. LOLA: Ornithine aspartate; MASLD: Metabolic-dysfunction associated steatotic liver disease.