Presepsin as a biomarker of bacterial translocation and an indicator for the prescription of probiotics in cirrhosis

doi:10.4254/wjh.v16.i5.822

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May 27, 2024 (publication date) through Nov 29, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. May 27, 2024; 16(5): 822-831
Published online May 27, 2024. doi: 10.4254/wjh.v16.i5.822

Table 2 Significant correlations between blood presepsin levels and gut microbiota taxa

Direct correlations			Inverse correlations
Taxon rank	Taxon	R, P value	Taxon rank	Taxon	R, P value
Phylum	Proteobacteria	0.316, 0.029	Family	Lachnospiraceae	0.447, 0.042¹
Class	Bacilli	0.470, 0.032¹		Propionibacteriaceae	-0.302, 0.038
	Gammaproteobacteria	0.351, 0.014	Genus	Fusicatenibacter	-0.297, 0.040
Family	Erysipelatoclostridiaceae	0.384, 0.007		Holdemanella	-0.315, 0.029
	Eubacteriaceae	0.340, 0.018
	Vibrionaceae	0.366, 0.010
	Xanthobacteraceae	0.363, 0.011
Genus	Escherichia-Shigella	0.338, 0.019
	Stenotrophomonas	0.365, 0.011
	Vibrio	0.346, 0.016

¹For the range of presepsin levels from 1 to 1000 pg/mL.

Citation: Efremova I, Maslennikov R, Poluektova E, Medvedev O, Kudryavtseva A, Krasnov G, Fedorova M, Romanikhin F, Zharkova M, Zolnikova O, Bagieva G, Ivashkin V. Presepsin as a biomarker of bacterial translocation and an indicator for the prescription of probiotics in cirrhosis. World J Hepatol 2024; 16(5): 822-831
URL: https://www.wjgnet.com/1948-5182/full/v16/i5/822.htm
DOI: https://dx.doi.org/10.4254/wjh.v16.i5.822