Non-alcoholic fatty liver disease and sleep disorders

Figure 1 The pathological mechanism of obstructive sleep apnea promotes the development of non-alcoholic fatty liver disease. Obstructive sleep apnea causes glucose and lipid metabolism disorders, intestinal flora disorder and hepatic inflammation through the sympathetic nervous system, endotoxemia and hepatic toll-like receptor-4. TL-R4: Toll-like receptor-4; lL-1R: Interleukin-1 receptor; IL-1β: Interleukin-1 β.