Yinhuang granule alleviates carbon tetrachloride-induced liver fibrosis in mice and its mechanism

Figure 2 Yinhuang granule decreased liver hydroxyproline content and hepatic collagen expression in carbon tetrachloride-treated mice. A: Liver hydroxyproline content (n = 6); B: Serum content of hyaluronic acid (n = 6); C: Liver Masson's trichrome staining. Arrows indicate collagen disposition; D: Liver Sirius red staining. Arrows indicate collagen disposition. (Original magnification ×100, upper images; partial enlarged pictures, down images). Data were expressed as mean ± SEM. ^bP < 0.01 vs control vehicle; ^cP < 0.05, ^dP < 0.01 vs carbon tetrachloride vehicle. CCl₄: Carbon tetrachloride; YHG: Yinhuang granule.