Yinhuang granule alleviates carbon tetrachloride-induced liver fibrosis in mice and its mechanism

Figure 1 Effects of Yinhuang granule on serum activities of alanine/aspartate aminotransferase and liver histological evaluation. A: Serum alanine aminotransferase activity; B: Serum aspartate aminotransferase activity; C: Liver H&E staining. Arrows indicate hepatic infiltration of immune cells, swelling and necrosis of hepatocytes. Typical images were chosen from each experimental group. (Original magnification ×100, upper images; partial enlarged pictures, down images). Data are expressed as mean ± SEM (n = 5). ^bP < 0.01 vs control vehicle; ^cP < 0.05 vs CCl₄ vehicle. CCl₄: Carbon tetrachloride. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.