Evaluation of autoimmune phenomena in patients with nonalcoholic fatty liver disease on the basis of liver pathology

Table 3 Comparison of biochemical indexes among the three groups

	NAFL (n = 36)	NASH (n = 51)	Cirrhosis (n = 17)	F/H	P value
FBG	5.65 (5.20, 6.17)	6.07 (5.49, 6.64)	5.04 (4.86, 6.87)	4.413	0.110
CHO	5.50 (4.72, 6.36)	5.71 (5.06, 6.88)	5.14 (4.24, 6.11)	3.614	0.164
TG	1.44 (0.97, 1.69)b	1.93 (1.46, 2.46)	1.25 (0.97, 1.46)c	21.567	0.000
HDL	1.47 (1.26, 1.79)	1.37 (1.24, 1.53)	1.42 (1.15, 1.56)	3.219	0.200
LDL	3.59 (2.08, 4.42)	3.82 (3.03, 4.57)	3.23 (2.54, 3.92)	4.738	0.094
ALT	31.55 (21.80, 63.45)d	83.50 (50.00, 156.60)	33.30 (16.95, 73.95)e	20.514	0.000
AST	24.00 (18.33, 35.10)	46.00 (34.10, 76.00)f	42.70 (24.35, 53.50)g	26.408	0.000
ALP	79.50 (68.00, 100.23)	77.80 (66.30, 87.30)	82.60 (70.20, 107.35)	0.866	0.648
GGT	89.95 (39.53, 129.03)	69.00 (45.50, 100.90)	58.80 (30.95, 93.45)	1.718	0.424
TBIL	15.10 (12.23, 25.15)	13.90 (12.20, 16.60)	17.81 (12.10, 22.75)	5.088	0.079
DBIL	1.70 (1.40, 3.85)	1.90 (1.40, 2.40)	2.20 (1.20, 2.95)	0.446	0.800
IgG	12.16 (10.64, 13.52)	10.95 (10.04, 13.09)	11.77 (9.83, 15.33)	2.586	0.275
IgM	0.89 (0.72, 1.21)	0.85 (0.60, 1.09)	1.07 (0.85, 1.36)	3.501	0.174
IgA	2.46 ± 0.89a	2.72 ± 0.88	3.21 ± 1.13	3.839	0.025

^aP = 0.02 vs cirrhosis group.

^bP < 0.001 vs cirrhosis group.

^cP = 0.001 vs NASH group.

^dP < 0.001 vs NASH group.

^eP = 0.004 vs NASH group.

^fP < 0.001 vs NAFL group.

^gP = 0.037 vs NAFL group.

FBG: Fasting blood glucose; CHO: Cholesterol; TG: Triglyceride; HDL: High density lipoprotein; LDL: Low density lipoprotein; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Glutamyl transferase TBIL: Total bilirubin; DBIL: Direct bilirubin.