Sensitivity of diagnosis of spontaneous bacterial peritonitis is higher with the automated cell count method

Table 6 Clinical and biochemical characteristics of positive-spontaneous bacterial peritonitis and negative-spontaneous bacterial peritonitis cases in cohort 2, n (%)/mean ± SD

	Negative-SBP (n = 52)	Positive-SBP (n = 33)	P value
Demographics and clinical characteristics
Male sex	21 (40)	17 (52)	0.37
Age (years)	55.0 ± 13.5	60.4 ± 14.8	0.08
Alcohol-related cirrhosis	45 (87)	29 (88)	0.16
Diabetes	6 (12)	7 (22)	0.23
Betablockers	16 (31)	13 (41)	0.48
Immunosuppression	0	1 (3)	0.38
SBP prophylaxis	24 (46)	5 (16)	0.005
Rifaximin	1 (2)	8 (25)	0.002
Main cause of admission
Elective LVP	52 (100)
Infection		17 (52)
Ascites		7 (21)
Jaundice		5 (15)
Encephalopathy		1 (3)
UGIB		1 (3)
AKI		2 (6)
Admission in ITU	0	7 (21)	< 0.001
Shock	0	7 (22)	< 0.001
Hospital mortality	0/52	14/33 (42)	< 0.001
Liver and renal function
Bilirubin (µmol/L)	42 ± 27	158 ± 164	< 0.001
Albumin (g/L)	30 ± 4	29 ± 5	0.23
INR	1.3 ± 0.2	1.8 ± 0.7	< 0.001
Ascites-Grade 31	49 (94)	20 (61)	< 0.001
Encephalopathy
Grade 0-1	52 (100)	17 (52)	< 0.001
Grade 2-3	0	16 (48%)

¹All other cases had grade-2 ascites.

SBP: Spontaneous bacterial peritonitis; LVP: Large volume paracentesis; UGIB: Upper gastrointestinal bleeding; AKI: Acute kidney injury; ITU: Intensive therapy unit; INR: International normalized ratio; MELD: Model for end-stage liver disease; UKELD: United Kingdom end-stage liver disease; CLIF-C ACLF: Chronic liver failure consortium acute-on-chronic liver failure.