Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma secondary to metabolic-dysfunction associated steatotic liver disease

Figure 2 Hepatic gene expression of autophagy markers. A: Autophagy-related factor LC3A/B; B: P62/sequestosome-1; C: Beclin-1; D: Enhancer of zeste homolog-2; E: Coactivator associated arginine methyltransferase-1. Data expressed as median (25^th-75^th percentile), Kruskal-Wallis test. Different letters indicate a significant difference between groups (P < 0.05). ^aP < 0.05, ^bP < 0.05. Different letters indicate a significant difference between groups. Becn1: Beclin-1; Carm1: Coactivator associated arginine methyltransferase-1; Ezh2: Enhancer of zeste homolog-2; HCC: Hepatocellular carcinoma; Map1 Lc3b: Autophagy-related factor LC3A/B; p62/Sqstm1: Sequestosome-1; RIF: Rifaximin.