Copyright
©The Author(s) 2023.
World J Hepatol. Aug 27, 2023; 15(8): 985-1000
Published online Aug 27, 2023. doi: 10.4254/wjh.v15.i8.985
Published online Aug 27, 2023. doi: 10.4254/wjh.v15.i8.985
Table 2 Univariate and multivariate logistic regression analysis of factors associated with metabolic associated fatty liver disease, n (%)
Variable | Category | Univariate analysis | Multivariable analysis | ||
Odds ratio (95%CI) | P value | Odds ratio (95%CI) | P value | ||
General information | |||||
Sex | Male(ref) | ||||
Female | 0.69 (0.58-0.84) | < 0.001 | 0.67 (0.57-0.80) | 0.001 | |
Age | 1.01 (1.01-1.02) | 0.001 | 1.01 (1.00–1.02) | 0.001 | |
BMI, kg/m2 | 1.46 (1.41-1.52) | < 0.001 | 1.45 (1.40-1.51) | < 0.001 | |
Systolic blood pressure, mmHg | 1.00 (0.99-1.00) | 0.360 | None | ||
Diastolic blood pressure, mmHg | 1.01 (1.00-1.02) | 0.007 | 1.01 (1.00–1.01) | 0.002 | |
Waist circumference, cm | 1.12 (1.11-1.14) | < 0.001 | 1.12 (1.11-1.14) | < 0.001 | |
Hip circumference, cm | 0.95 (0.93-0.96) | < 0.001 | 0.95 (0.93-0.96) | < 0.001 | |
Smoke | Never (ref) | 0.409 | None | ||
Always | 1.18 (0.90-1.56) | 0.236 | None | ||
Smoke in the past | 1.07 (0.80-1.43) | 0.667 | None | ||
Passive exposure to secondhand smoke | 1.15 (0.80-1.65) | 0.464 | None | ||
Alcohol consumption | No(ref) | ||||
Yes | 0.89 (0.78-1.01) | 0.061 | 1.11 (0.99-1.26) | 0.082 | |
Diabetes | No(ref) | ||||
Yes | 1.16 (0.91-1.49) | 0.231 | None | ||
≥ 2 metabolic abnormalities | No(ref) | ||||
Yes | 3.38 (3.00-3.82) | < 0.001 | 3.38 (2.99-3.81) | < 0.001 | |
Take the initiative to acquire medical knowledge | No(ref) | ||||
Yes | 1.14 (1.02-1.26) | 0.017 | 1.14 (1.03-1.27) | 0.014 | |
Laboratory inspection | |||||
TG, mmol/L | 1.31 (1.15-1.49) | < 0.001 | 1.33 (1.27-1.40) | < 0.001 | |
TC, mmol/L | 1.09 (0.81-1.45) | 0.578 | None | ||
LDL- C, mmol/L | 1.00 (0.74-1.35) | 0.997 | None | ||
HDL-C, mmol/L | 0.50 (0.33-0.73) | < 0.001 | 0.58 (0.47-0.71) | < 0.001 | |
TBIL, μmol/L | 1.01 (1.00-1.02) | 0.044 | 0.98 (0.98-0.99) | < 0.001 | |
AST, U/L | 0.98 (0.97-0.98) | < 0.001 | 1.01 (1.01-1.01) | < 0.001 | |
ALT, U/L | 1.02 (1.02-1.03) | < 0.001 | 1.02 (1.02-1.02) | < 0.001 | |
A/G | 1.85 (1.53-2.25) | < 0.001 | 0.99 (0.92-1.08) | 0.884 | |
BUN, mmol/L | 0.98 (0.94-1.02) | 0.388 | None | ||
FPG, mmol/L | 0.97 (0.91-1.04) | 0.426 | None | ||
HbA1c (%) | 1.35 (1.20-1.52) | < 0.001 | 1.52 (1.47-1.57) | < 0.001 | |
Total bile acid, μmol/L | 1.00 (1.00-1.01) | 0.395 | None | ||
SUA, μmol/L | 1.00 (1.00-1.01) | < 0.001 | 1.01 (1.01-1.01) | < 0.001 | |
Platelets (×109/L) | 1.00 (1.00-1.00) | < 0.001 | 1.00 (1.00-1.00) | < 0.001 | |
Creatinine, μmol/L | 0.99 (0.99-1.00) | < 0.001 | 0.99 (0.99-0.99) | < 0.001 | |
Lifestyle management | |||||
Inappetence | Never(ref) | 0.597 | None | ||
Occasionally | 1.13 (0.84-1.52) | 0.409 | None | ||
Often | 1.16 (0.86-1.57) | 0.322 | None | ||
Do you often eat late night snacks | Never(ref) | 0.529 | None | ||
Occasionally | 1.33 (0.78-2.28) | 0.288 | |||
Often | 1.37 (0.79-2.35) | 0.260 | |||
Crapulent | No(ref) | ||||
Yes | 0.93 (0.73-1.20) | 0.586 | None | ||
Food preference | Light (ref) | 0.868 | None | ||
Briny | 0.97 (0.85-1.10) | 0.617 | |||
Unclear | 0.99 (0.85-1.14) | 0.874 | |||
Drink beverage | Never (ref) | 0.015 | 0.004 | ||
Occasionally | 2.66 (1.37-5.18) | 0.004 | 1.01 (0.85-1.20) | 0.917 | |
Often | 2.69 (1.36-5.32) | 0.004 | 0.32 (0.17-0.63) | 0.001 | |
Exercise frequency | 1-2 times/wk (ref) | 0.048 | 0.025 | ||
3-5 times/wk | 1.20 (1.03-1.40) | 0.017 | 0.95 (0.84-1.08) | 0.429 | |
> 5 times/wk | 1.14 (1.00-1.30) | 0.049 | 0.82 (0.71-0.95) | 0.009 | |
Exercise training | 0.39 (0.04-3.58) | 0.404 | None | ||
Exercise duration | < 30 min (ref) | 0.049 | 0.045 | ||
30-60 min | 0.81 (0.68-0.96) | 0.017 | 1.07 (0.94-1.22) | 0.283 | |
> 60 min | 0.87 (0.76-1.00) | 0.045 | 1.24 (1.04-1.47) | 0.015 | |
Labor intensity | Light physical labor (ref) | 0.049 | 0.026 | ||
Moderate physical labor | 0.80 (0.66-0.97) | 0.024 | 0.78 (0.65-0.95) | 0.013 | |
Heavy physical labor | 0.79 (0.51-1.21) | 0.273 | 0.77 (0.50-1.18) | 0.226 | |
Psychological states | |||||
Irritability | Never (ref) | 0.637 | None | ||
Occasionally | 1.01 (0.89-1.15) | 0.851 | |||
Often | 1.14 (0.87-1.50) | 0.346 | |||
Tense and unrelaxed | Never (ref) | 0.806 | None | ||
Occasionally | 0.95 (0.820-1.11) | 0.351 | |||
Often | 0.96 (0.69-1.35) | 0.828 | |||
Anxious | Never (ref) | 0.076 | 0.091 | ||
Occasionally | 0.92 (0.78-1.08) | 0.290 | 0.96 (0.85-1.07) | 0.447 | |
Often | 1.38 (0.91-2.08) | 0.127 | 1.31 (1.00-1.73) | 0.052 | |
Depress | Never (ref) | 0.211 | None | ||
Occasionally | 1.09 (0.92-1.29) | 0.320 | |||
Often | 0.77 (0.49-1.21) | 0.264 | |||
Sleep | Well (ref) | 0.221 | None | ||
Moderate | 0.98 (0.82-1.16) | 0.791 | |||
Bad | 0.89 (0.74-1.07) | 0.225 |
- Citation: Huang XJ, Yin M, Zhou BQ, Tan XY, Xia YQ, Qin CX. Impact renaming non-alcoholic fatty liver disease to metabolic associated fatty liver disease in prevalence, characteristics and risk factors. World J Hepatol 2023; 15(8): 985-1000
- URL: https://www.wjgnet.com/1948-5182/full/v15/i8/985.htm
- DOI: https://dx.doi.org/10.4254/wjh.v15.i8.985