Randomized intervention and outpatient follow-up lowers 30-d readmissions for patients with hepatic encephalopathy, decompensated cirrhosis

Table 1 Characteristic features of index admission by readmission status, n (%)

	Total	Not readmitted (n = 159)	Readmitted (n = 81)	P value
Index admission characteristics
Reasons for admission1
Acute kidney injury	65, 27.08	41, 25.79	24, 29.63	0.54
Hyponatremia	16, 6.67	11, 6.92	5, 6.17	1.00
Hepatic encephalopathy	45, 18.75	26, 16.35	19, 23.46	0.22
Volume overload	111, 46.25	81, 50.94	30, 37.04	0.06
Variceal bleed	42, 17.50	31, 19.50	11, 13.58	0.29
Lower GI bleed	19, 7.92	11, 6.92	8, 9.88	0.45
SBP	21, 8.75	14, 8.81	7, 8.64	1.00
Complications of cirrhosis during admission1
Presence of AKI	80, 33.33	50, 31.45	30, 37.04	0.39
HE	49, 20.42	31, 19.50	18, 22.22	0.62
Ascites	139, 57.92	95, 59.75	44, 54.32	0.49
Variceal bleeding	37, 15.42	26, 16.35	11, 13.58	0.71
SBP	16, 6.67	12, 7.55	4, 4.94	0.59
HRS	14, 5.83	8, 5.03	6, 7.41	0.56
Coagulopathy	56, 23.33	36, 22.64	20, 24.69	0.75
Portal hypertension	46, 19.17	34, 21.38	12, 14.81	0.30
HPS	15, 6.25	8, 5.03	7, 8.64	0.27
HCC	11, 4.58	6, 3.77	5, 6.17	0.51
Procedures performed during admission1
EGD	136, 56.67	92, 57.86	44, 54.32	0.68
Paracentesis	115, 47.92	73, 45.91	42, 51.85	0.41
Emergent TIPS	10, 4.17	9, 5.66	1, 1.23	0.17
HD	15, 6.25	7, 4.40	8, 9.88	0.16
Colonoscopy/flex sig	24, 10.00	18, 11.32	6, 7.41	0.37
Disposition1
Home	159, 66.25	107, 67.30	52, 64.20	0.66
Home with Home Health Newly Arranged	39, 16.25	24, 15.09	15, 18.52
Home with Home Health Previously Arranged	3, 1.25	2, 1.26	1, 1.23
SNF newly Arranged	21, 8.75	16, 10.06	5, 6.17
SNF Previously Arranged	11, 4.58	5, 3.14	6, 7.41
Left Against Medical Advice	2, 0.83	1, 0.63	1, 1.23
Transfer (long term acute care hospital)	3, 1.25	2, 1.26	1, 1.23
Homeless	2, 0.83	2, 1.26	0, 0.00

¹Patient can have more than one of variable listed.

SBP: Spontaneous bacterial peritonitis; AKI: Acute kidney injury; HE: Hepatic encephalopathy; HRS: Hepatorenal syndrome; HPS: Hepato-pulmonary syndrome; HCC: Hepatocellular carcinoma; EGD: Esophago-gastro-duodenoscopy; GI: Gastrointestinal; TIPS: Transjugular intrahepatic portosystemic shunt; HD: Hemodialysis; SNF: Skilled Nursing Facility.