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©The Author(s) 2023.
World J Hepatol. Apr 27, 2023; 15(4): 554-563
Published online Apr 27, 2023. doi: 10.4254/wjh.v15.i4.554
Published online Apr 27, 2023. doi: 10.4254/wjh.v15.i4.554
Table 2 Pathological characteristics of hepatocellular carcinoma in liver transplant, n (%)
| Variable | COVID, n = 518 | Pre-COVID, n = 675 | Pvalue |
| Number of tumors | |||
| 1 | 229 (44) | 333 (49) | |
| 2 | 116 (22) | 146 (22) | |
| 3 | 80 (15) | 77 (11) | |
| 4 | 36 (6.9) | 47 (7.0) | |
| 5 | 22 (4.2) | 33 (4.9) | |
| 6 | 31 (6.0) | 38 (5.6) | |
| Tumor numbers > 3 | 89 (17) | 118 (17) | 0.89 |
| Outside UCSF criteria | 131 (25) | 178 (26) | 0.71 |
| Outside Milan criteria | 203 (39) | 262 (39) | 0.84 |
| Tumor max size, cm median (IQR) | 2.80 (1.80, 4.00) | 2.90 (1.90, 4.00) | 0.92 |
| Worst tumor histology | |||
| Complete tumor necrosis | 132 (25) | 185 (27) | 0.5 |
| Moderate differentiated | 265 (51) | 344 (51) | |
| Poorly differentiated | 26 (5.0) | 41 (6.1) | |
| Well differentiated | 95 (18) | 105 (16) | |
| Vascular invasion | 6 (1.2) | 11 (1.6) | 0.019 |
| Macro | |||
| Micro | 77 (15) | 65 (9.6) | |
| None | 435 (84) | 599 (89) | |
| Lymph node involvement | 8 (1.5) | 4 (0.6) | 0.1 |
| Extra hepatic spread | 7 (1.4) | 6 (0.9) | 0.76 |
| Intrahepatic metastasis | 42 (8.1) | 36 (5.3) | 0.066 |
| Previous treatment for HCC | 511 (99) | 657 (97) | 0.21 |
| High risk features | 174 (34) | 198 (29) | 0.12 |
- Citation: Lee IS, Okumura K, Misawa R, Sogawa H, Veillette G, John D, Diflo T, Nishida S, Dhand A. Inferior outcomes of liver transplantation for hepatocellular carcinoma during early-COVID-19 pandemic in the United States. World J Hepatol 2023; 15(4): 554-563
- URL: https://www.wjgnet.com/1948-5182/full/v15/i4/554.htm
- DOI: https://dx.doi.org/10.4254/wjh.v15.i4.554