Extended criteria brain-dead organ donors: Prevalence and impact on the utilisation of livers for transplantation in Brazil

Table 1 Descriptive analysis of donor organ characteristics per year, n (%)

Variable (year)	2017	2018	2019	2020	Total
Donor's place of origin
Local	121 (48.21%)	180 (38.88%)	261 (57.36%)	257 (57.11%)	819 (50.59%)
Regional	67 (26.69%)	149 (32.18%)	128 (28.13%)	131 (29.11%)	475 (29.34%)
Nacional	63 (25.10%)	134 (28.94%)	66 (14.51%)	62 (13.78%)	325 (20.07%)
Gender, female	119 (47.60%)	193 (41.87%)	190 (41.76%)	174 (38.75%)	676 (41.86%)
Blood type (ABO system)
A	82 (32.93%)	150 (32.47%)	157 (34.58%)	168 (37.42%)	557 (34.51%)
B	38 (15.26%)	52 (11.26%)	48 (10.57%)	36 (8.02%)	174 (10.78%)
AB	11 (4.42%)	16 (3.46%)	25 (5.51%)	7 (1.56%)	59 (3.66%)
O	118 (47.39%)	244 (52.81%)	224 (49.34%)	238 (53.01%)	824 (51.05%)
Race
Black	39 (15.54%)	42 (9.07%)	57 (12.53%)	46 (10.22%)	184 (11.37%)
Mixed-race	80 (31.87%)	164 (35.42%)	159 (34.95%)	178 (39.56%)	581 (35.89%)
White	123 (49.00%)	253 (54.64%)	235 (51.65%)	223 (49.56%)	834 (51.51%)
Others	9 (3.59%)	4 (0.86%)	4 (0.88%)	3 (0.67%)	20 (1.24%)
Age (categories)
< 40 yr	48 (19.12%)	90 (19.44%)	104 (22.86%)	115 (25.56%)	357 (22.05%)
40 yr to 49 yr	58 (23.11%)	102 (22.03%)	91 (20.00%)	106 (23.56%)	357 (22.05%)
50 yr to 59 yr	77 (30.68%)	134 (28.94%)	136 (29.89%)	123 (27.33%)	470 (29.03%)
60 yr to 69 yr	53 (21.12%)	99 (21.38%)	105 (23.08%)	82 (18.22%)	339 (20.94%)
≥ 70 yr	15 (5.98%)	38 (8.21%)	19 (4.18%)	24 (5.33%)	96 (5.93%)
Age (yr)	50.50 (14.52)	50.77 (15.07)	50.00 (14.09)	47.85 (15.03)	49.70 (14.74)
ICU stay > 5 d	105 (41.83%)	187 (40.39%)	178 (39.12%)	200 (44.44%)	670 (41.38%)
Cause of death
Cerebrovascular accident	175 (70.00%)	294 (63.50%)	298 (65.49%)	277 (61.56%)	1044 (64.52%)
Trauma	43 (17.20%)	113 (24.41%)	101 (22.20%)	121 (26.89%)	378 (23.36%)
Hypoxia	24 (9.60%)	45 (9.72%)	40 (8.79%)	41 (9.11%)	150 (9.27%)
Others	8 (3.20%)	11 (2.38%)	16 (3.52%)	11 (2.44%)	46 (2.84%)
BMI (kg/m2)	27.28 (5.04)	26.65 (5.00)	26.69 (4.57)	26.31 (4.20)	26.66 (4.68)
Alcoholism	75 (29.88%)	148 (31.97%)	115 (25.27%)	103 (22.89%)	441 (27.24%)
Cardiorespiratory arrest	61 (24.30%)	99 (21.38%)	82 (18.02%)	77 (17.11%)	319 (19.70%)
Vasoactive drugs in the donor	221 (88.05%)	422 (91.14%)	408 (89.67%)	405 (90.00%)	1456 (89.93%)
AST (U/L)1	56.00 (32.00; 102.00)	64.50 (37.00; 125.00)	74.00 (39.00; 151.00)	74.00 (39.40; 141.00)	68.00 (38.00; 132.00)
ALT (U/L)1	47.00 (24.00; 93.00)	49.00 (29.00; 96.00)	45.70 (26.00; 103.00)	47.00 (28.00; 89.00)	47.00 (27.00; 96.00)
GGT (U/L)1	84.00 (34.00; 182.00)	94.50 (38.55; 200.00)	83.50 (39.00; 207.00)	84.00 (36.00; 197.50)	87.00 (37.00; 198.00)
Total bilirubin (mg/dL)1	0.50 (0.32; 0.91)	0.50 (0.30; 0.91)	0.55 (0.35; 0.97)	0.52 (0.35; 0.90)	0.52 (0.33; 0.92)

¹Categorical variables are presented in absolute numbers (frequency as a percentage). Continuous variables are presented as mean (standard deviation) or median (quartiles).

ICU: Intensive care unit; BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transferase.