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©The Author(s) 2023.
World J Hepatol. Feb 27, 2023; 15(2): 237-254
Published online Feb 27, 2023. doi: 10.4254/wjh.v15.i2.237
Published online Feb 27, 2023. doi: 10.4254/wjh.v15.i2.237
Table 4 Comparison of pathological features of chronic hepatitis B patients with and without nonalcoholic fatty liver disease, n (%)
| Pathological features | Total | NAFLD | No NAFLD | P value |
| (n = 456) | (n = 152) | (n = 304) | ||
| Fibrosis | 0.045 | |||
| F0 | 109 (23.9) | 30 (19.7) | 79 (26) | |
| F1 | 129 (28.3) | 36 (23.7) | 93 (30.6) | |
| F2 | 93 (20.4) | 41 (27) | 52 (17.1) | |
| F3 | 58 (12.7) | 21 (13.8) | 37 (12.2) | |
| F4 | 67 (14.7) | 24 (15.8) | 43 (14.1) | |
| Steatosis | ||||
| 0 | 304 (66.7) | 304 (100) | ||
| 1 | 89 (19.5) | 89 (58.6) | ||
| 2 | 48 (10.5) | 48 (31.6) | ||
| 3 | 15 (3.3) | 15 (9.9) | ||
| Portal tract inflammation | < 0.001 | |||
| 0 | 35 (7.7) | 8 (5.3) | 27 (8.9) | |
| 1 | 275 (60.3) | 79 (52) | 196 (64.5) | |
| 2 | 117 (25.7) | 50 (32.9) | 67 (22) | |
| 3 | 29 (6.3) | 15 (9.9) | 14 (4.6) | |
| Lobular inflammation | 0.13 | |||
| 0 | 91 (20) | 28 (18.4) | 63 (20.7) | |
| 1 | 315 (69.1) | 101 (66.4) | 214 (70.4) | |
| 2 | 50 (11) | 23 (15.1) | 27 (8.9) | |
| Ballooning degeneration | 0.004 | |||
| 0 | 153 (33.6) | 58 (38.2) | 165 (54.3) | |
| 1 | 195 (42.8) | 61 (40.1) | 96 (31.6) | |
| 2 | 108 (23.7) | 33 (21.7) | 43 (14.1) | |
| NASH | 32 (21.1) | 32 (21.1) | ||
| NAS score | 1.7 ± 1.2 | 2.7 ± 1.2 | 1.2 ± 0.8 | < 0.001 |
- Citation: Tan YW, Wang JM, Zhou XB. Baseline hepatocyte ballooning is a risk factor for adverse events in patients with chronic hepatitis B complicated with nonalcoholic fatty liver disease. World J Hepatol 2023; 15(2): 237-254
- URL: https://www.wjgnet.com/1948-5182/full/v15/i2/237.htm
- DOI: https://dx.doi.org/10.4254/wjh.v15.i2.237