Study of liver cirrhosis over twenty consecutive years in adults in Southern China

Figure 3 Temporal trends of viral hepatitis and other major etiologies in 2001-2020. The proportion of hepatitis B virus-liver cirrhosis (HBV-LC) decreased dramatically during the 2001-2010 period but fluctuated and decreased slightly during the 2011-2020 period. Meanwhile, proportions of alcoholic-LC and autoimmune or cholestatic-LC have increased during the 20-year period. Hepatitis C virus (HCV)-LC and (HBV + HCV)-LC have not shown explicit trends. The Cochran-Armitage test for P trend found no statistical significance (P > 0.05) when comparing proportions in separated years (P > 0.05). HBV: Hepatitis B virus; HCV: Hepatitis C virus.