Evaluation of a protocol for rifaximin discontinuation in critically ill patients with liver disease receiving broad-spectrum antibiotic therapy

Table 4 Negative binomial multivariable model

(n = 60)	DAFD ratio (95%CI)
Group assignment (protocol)	0.78 (0.39, 1.56)
Deep sedation (yes)	0.89 (0.39, 2.02)
Gastrointestinal bleeding (yes)	0.65 (0.32, 1.31)
MELD-Na (per unit increase)	0.97 (0.94, 1.01)
Mechanical ventilation duration (per day)	0.79 (0.72, 0.87)

Reference value listed in parentheses. DAFD: Days alive and free of delirium and coma to day 14; MELD-Na: Model for End-Stage Liver Disease Sodium score; CI: Confidence interval.