Liver disease epidemiology and burden in patients with alterations in plasma protein metabolism: German retrospective insurance claims analysis

Figure 1 Selection of patient cohorts. ¹In total, 135 patients had only one outpatient alterations in plasma protein metabolism (APPM) diagnosis and therefore did not meet these criteria; ²In total, 42 patients with fibrosis in the APPM cohort progressed to cirrhosis during follow-up; and ³In total, 280 patients with fibrosis in the control cohort progressed to cirrhosis during follow-up. ICD-10-GM: German Modification of the International Classification of Diseases-10^th Revision.