Retrospective Study
Copyright ©The Author(s) 2023.
World J Hepatol. Oct 27, 2023; 15(10): 1127-1139
Published online Oct 27, 2023. doi: 10.4254/wjh.v15.i10.1127
Table 1 Demographics and baseline characteristics, n (%)
Patients with APPM and liver disease: APPM cohort, n = 2680
Patients without APPM and with liver disease: Control cohort, n = 26299
All patients, n = 2680
Patients with fibrosis, n = 96
Patients with cirrhosis, n = 26261
Total observed patient-years6118283594470261
Median follow-up, yr (IQR)1.5 (0.4-3.7)2.3 (0.8-4.7)1.5 (0.4-3.7)2.0 (0.5-4.4)
Female sex2840 (31.3)41 (42.7)815 (31.0)8595 (32.7)
Median age, yr (IQR)363.0 (54.0-73.0)64.5 (53.0-76.5)63.0 (54.0-73.0)65.0 (56.0-76.0)
0-14 yr14 (0.5)6 (6.3)10 (0.4)49 (0.2)
15-29 yr10 (0.4)010 (0.4)156 (0.6)
30-44 yr183 (6.8)10 (10.4)177 (6.7)1420 (5.4)
45-59 yr818 (30.5)21 (21.9)814 (31.0)7516 (28.6)
60-74 yr1046 (39.0)31 (32.3)1029 (39.2)9564 (36.4)
75-89 yr577 (21.5)25 (26.0)557 (21.2)7090 (27.0)
≥ 90 yr32 (1.2)3 (3.1)29 (1.1)504 (1.9)
With care needs4547 (20.4)33 (34.3)528 (20.1)4934 (18.8)
Median CCI5 (IQR)3.0 (1.0-5.0)4.0 (1.5-6.0)3.0 (1.0-5.0)3.0 (1.0-5.0)
Most common liver-related comorbidities
“Other” liver disease6679 (25.3)26 (27.1)669 (25.5)6298 (23.9)
Non-alcoholic steatohepatitis17 (0.6)1 (1.0)16 (0.6)150 (0.6)
Chronic hepatitis12 (0.5)012 (0.5)163 (0.6)
Respiratory system-related comorbidities827 (30.9)41 (42.7)806 (30.7)8333 (31.7)
Most common comorbidities
Hypertension1751 (65.3)64 (66.7)1710 (65.1)17278 (65.7)
Type 2 diabetes mellitus1103 (41.2)40 (41.7)1082 (41.2)10766 (40.9)
Dyslipidaemia832 (31.0)35 (36.5)813 (31.0)8932 (34.0)
Alcohol-related disorders7650 (24.3)17 (17.7)649 (24.7)6127 (23.3)
Heart failure605 (22.6)21 (21.9)591 (22.5)6071 (23.1)