Challenges and dilemmas in pediatric hepatic Wilson’s disease

doi:10.4254/wjh.v15.i10.1109

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Oct 27, 2023 (publication date) through Mar 6, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 27, 2023; 15(10): 1109-1126
Published online Oct 27, 2023. doi: 10.4254/wjh.v15.i10.1109

Table 4 Risk factors for side effects of drug therapy in Wilson’s disease

Side effect of drugs	Risk factor	How to differentiate
Neurological worsening with D-penicillamine or trientine	Pre-existing neurological Wilson disease	Exchangeable copper and relative exchangeable copper
Cytopenia due to D-penicillamine	Co-existing hypersplenism due to portal hypertension	Bone marrow biopsy

Citation: Ghosh U, Sen Sarma M, Samanta A. Challenges and dilemmas in pediatric hepatic Wilson’s disease. World J Hepatol 2023; 15(10): 1109-1126
URL: https://www.wjgnet.com/1948-5182/full/v15/i10/1109.htm
DOI: https://dx.doi.org/10.4254/wjh.v15.i10.1109