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©The Author(s) 2023.
World J Hepatol. Oct 27, 2023; 15(10): 1109-1126
Published online Oct 27, 2023. doi: 10.4254/wjh.v15.i10.1109
Published online Oct 27, 2023. doi: 10.4254/wjh.v15.i10.1109
Table 2 Diagnostic tests for suspected Wilson disease patients and asymptomatic siblings
| Parameters | Tests for suspected patients | Tests for asymptomatic siblings |
| Clinical examination | Yes | Yes |
| Liver function test | Yes | Yes |
| Slit lamp examination for Kayser–Fleischer ring | Yes | Yes |
| Serum ceruloplasmin | Yes | Yes |
| 24 h urine copper | Yes | Yes |
| Genetic analysis for ATP7B gene mutation analysis | Yes, if feasible | Yes (if proband sample is available) |
| Liver biopsy | Yes, ancillary test | No |
| Hepatic copper | Yes, to be done in cases of ambiguity | No |
- Citation: Ghosh U, Sen Sarma M, Samanta A. Challenges and dilemmas in pediatric hepatic Wilson’s disease. World J Hepatol 2023; 15(10): 1109-1126
- URL: https://www.wjgnet.com/1948-5182/full/v15/i10/1109.htm
- DOI: https://dx.doi.org/10.4254/wjh.v15.i10.1109