Prognostic role of ring finger and WD repeat domain 3 and immune cell infiltration in hepatocellular carcinoma

Table 3 Univariate Cox regression analysis in hepatocellular carcinoma

Characteristics	Total, n	Univariate analysis
		Hazard ratio (95%CI)	P value
Pathologic stage	349
I	173
II	86	1.417 (0.868-2.312)	0.164
III	85	2.734 (1.792-4.172)	< 0.001
IV	5	5.597 (1.726-18.148)	0.004
Child-Pugh grade	240
A	218
B	21	1.595 (0.757-3.361)	0.219
C	1	2.138 (0.294-15.544)	0.453
Fibrosis Ishak score	214
0	75
1/2	31	0.935 (0.437-2.002)	0.864
3/4	28	0.698 (0.288-1.695)	0.428
5/6	80	0.737 (0.410-1.325)	0.308
Histologic grade	368
G1	55
G2	178	1.162 (0.686-1.969)	0.576
G3	123	1.185 (0.683-2.057)	0.545
G4	12	1.681 (0.621-4.549)	0.307
RFWD3	373	1.557 (1.148-2.110)	0.004

CI: Confidence interval; RFWD3: Ring finger and WD repeat domain 3.