Assessment of circulating levels of microRNA-326, microRNA-424, and microRNA-511 as biomarkers for hepatocellular carcinoma in Egyptians

doi:10.4254/wjh.v14.i8.1562

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Aug 27, 2022 (publication date) through Nov 12, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Aug 27, 2022; 14(8): 1562-1575
Published online Aug 27, 2022. doi: 10.4254/wjh.v14.i8.1562

Table 6 Studied miRNA associations with response to treatment according to modified response evaluation criteria in solid tumors

Response to treatment mRECIST	Stationary, n = 4 (5.7%)	Partial response, n = 7 (10.0%)	Complete response, n = 34 (48.6%)	Progressive disease, n = 6 (8.6%)	P value
miRNA-326	11.5 (2.1- 142.6)	31.1 (6.9- 209.4)	27.4 (10.0- 155.2)	69.6 (17.7- 197.9)	0.5
miRNA-511	3.8 (0.8- 10.5)	1.2 (0.3- 4.2)	1.0 (0.2- 1.5)	0.6 (0.1- 1.3)	0.05^a
miRNA-424	4.9 (3.0- 8.6)	4.8 (2.1- 5.1)	5.4 (2.6- 13.1)	4.6 (3.1- 15.2)	0.8

mRECIST: Modified Response Evaluation Criteria in Solid Tumors.

^aP value < 0.05 is significant.

Citation: Youssef SS, Elfiky A, Nabeel MM, Shousha HI, Elbaz T, Omran D, Marie MS, Elzahry MA, Abul-Fotouh A, Hashem A, Guda MF, Abdelaziz AO. Assessment of circulating levels of microRNA-326, microRNA-424, and microRNA-511 as biomarkers for hepatocellular carcinoma in Egyptians. World J Hepatol 2022; 14(8): 1562-1575
URL: https://www.wjgnet.com/1948-5182/full/v14/i8/1562.htm
DOI: https://dx.doi.org/10.4254/wjh.v14.i8.1562