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World J Hepatol. Aug 27, 2022; 14(8): 1550-1561
Published online Aug 27, 2022. doi: 10.4254/wjh.v14.i8.1550
Table 2 Summary of laboratory values and post-operative outcomes comparing patients with post-hepatectomy hypophosphatemia and normophosphatemia
Mean nadir phosphate, mg/dLa
Mean INRa
Length of stay, d
Post-hepatectomy liver failure
Any morbidity
30 d mortality
No
Ref.
PHH
NP
P value
PHH
NP
P value
PHH
NP
P value
PHH
NP
P value
PHH
NP
P value
PHH
NP
P value
1Buell et al[14], 19982.1 ± 0.1b 3.0 ± 0.2b < 0.05NR16.22 ± 12.0911.22 ± 7.03NRNR17/21 (81)4/14 (29)< 0.051/21 (5)0/14 (0)NR
2George et al[11], 1992NRNRNR1/44 (2)0/0NA11/44 (25)0/0 (0)NANR
3Giovannini et al[12], 20021.7 ± 0.8 (POD3)NRNRNRNRMild-moderate: 4/23 (17) Severe: 9/15 (60)3/21 (14)< 0.001cMild-moderate: 1/23 (4) Severe: 3/12 (20)1/21 (5)NR
4Hallet et al[10], 20161.52 ± 0.31d 2.72 ± 0.74d< 0.011.51 ± 0.371.53 ± 0.910.837 (6-10)7 (5-11)0.5544/223 (19.7)20/179 (11.2)0.02Major morbidity: 13/223 (5.8)Major morbidity: 12/179 (6.7)0.569/223 (4.0)4/179 (2.2)0.31
5Serrano et al[38], 20192.00e (recorded at median 1.6 d post-operatively)NR7.2 ± 3.4eNR10/161 (6.2)NRAny morbidity > 30 d: 19/161 (11.8)NRNR
6Squires et al[13], 20142.2 [1.7-2.8]NRNR Moderate: 8.0% Severe: 8.5% Profound: 3.4%f12.3%f0.008Major morbidity: Moderate: 20.1% Severe: 19.5% Profound: 16.7%f30.3%f0.037Moderate: 3.8% Severe: 2.8% Profound: 0%6.5%0.010
7Tan et al[39], 20032.6 (range 1.3-5.0)NRNRNRNRAny morbidity: 8/95 (8.4)NRNR
8Yuan et al[40], 20101.89 ± 0.72 (POD3)NRMild: 1.51 ± 0.26 Moderate: 1.43 ± 0.19 Severe: 1.95 ± 0.40NR< 0.001gNR14/100 (14)0/2 (0)NRNRNR