Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans

doi:10.4254/wjh.v14.i7.1408

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 27, 2022; 14(7): 1408-1420
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1408

Table 2 Prevalence of the type of dyslipidemias in West Mexico populations

Dyslipidemia	Native American ancestry		Mestizos (low-to-high European ancestry)					Total WMX (n = 884)	P value
Dyslipidemia	NAH (n = 84)	WXK (n = 106)	TPC (n = 184)	GDL (n = 321)	CUQ (n = 131)	VP (n = 32)	SMA (n = 26)	Total WMX (n = 884)	P value
HChol	6 (7.1)	41 (38.7)	139 (75.5)	113 (35.2)	43 (32.8)	21 (65.6)	11 (42.3)	374 (42.3)	0.001^a
HTG	35 (41.7)	36 (34.0)	94 (51.1)	116 (36.1)	49 (37.4)	15 (46.9)	12 (46.2)	357 (40.4)	0.001^b
High LDL-c	13 (15.5)	43 (40.6)	137 (74.5)	72 (22.4)	24 (18.3)	21 (65.6)	7 (26.9)	317 (35.8)	0.003^a
HALP	42 (50.0)	28 (26.4)	87 (47.3)	112 (34.9)	45 (34.3)	5 (15.6)	15 (57.7)	334 (37.8)	0.002^c

^aTepic (TPC) vs the other groups.

^bTPC vs Wixárika (WXK) & Cuquio (CUQ) group.

^cVilla Purificación & WXK vs the other groups.

The Chi-square test was the statistical approach. Values are presented as number of cases and percentage. NAH: Nahua indigenous group; WXK: Wixárika indigenous group; TPC: Tepic; GDL: Guadalajara; CUQ: Cuquio; VP: Villa Purificación; SMA: San Miguel el Alto; WMX: West Mexico; HChol: Hypercholesterolemia; HTG: Hypertriglyceridemia; HALP: Hypoalphalipoproteinemia.

Citation: Torres-Valadez R, Roman S, Ojeda-Granados C, Gonzalez-Aldaco K, Panduro A. Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans. World J Hepatol 2022; 14(7): 1408-1420
URL: https://www.wjgnet.com/1948-5182/full/v14/i7/1408.htm
DOI: https://dx.doi.org/10.4254/wjh.v14.i7.1408