Copyright
©The Author(s) 2022.
World J Hepatol. Jul 27, 2022; 14(7): 1382-1397
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1382
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1382
Table 3 Top disease functions for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis identified by Ingenuity Pathway Analysis
| Top disease functions in NAFLD vs healthy control | P values |
| Inflammatory response | 1.67E-03 |
| Liver lesion | 6.59E-05 |
| Cell movement of epithelial cells | 3.88E-04 |
| Activation of cells | 5.30E-04 |
| Synthesis of lipid | 5.49E-08 |
| Accumulation of lipid | 6.12E-04 |
| Concentration of lipid | 2.38E-06 |
| Fibrosis | 3.75E-05 |
| Secretion of lipid | 1.06E-03 |
| Hepatic injury | 1.54E-04 |
| Organismal injury and abnormalities | 5.10E-16 |
| Cancer | 3.47E-15 |
| Dermatologic diseases and conditions | 5.20E-11 |
| Metabolic disease | 6.69E-10 |
| Lipid metabolism | 8.09E-12 |
| Molecular transport | 7.06E-12 |
| Small molecule biochemistry | 9.86E-11 |
| Cell death and survival | 5.05E-8 |
| Cellular movement | 6.28E-8 |
| Adipogenesis | 1.31E-7 |
- Citation: Aljabban J, Rohr M, Syed S, Khorfan K, Borkowski V, Aljabban H, Segal M, Mukhtar M, Mohammed M, Panahiazar M, Hadley D, Spengler R, Spengler E. Transcriptome changes in stages of non-alcoholic fatty liver disease. World J Hepatol 2022; 14(7): 1382-1397
- URL: https://www.wjgnet.com/1948-5182/full/v14/i7/1382.htm
- DOI: https://dx.doi.org/10.4254/wjh.v14.i7.1382