Alfapump® implantable device in management of refractory ascites: An update

Table 2 General complications after implantation of alfapump^®: Acute kidney injury and peritoneal and urinary tract infections

Ref.	Patients (n)	AKI occurrence during follow-up	Variation in creatinine levels before vs after implantation	Peritoneal infections (n episodes)	Urinary tract infections (n episodes)
Bellot et al[13], 2013	40	13 episodes, 11 patients	106 vs 127 µmol/L at 3 mo (P = NA) 105 µmol/L at 6 mo (P = NA)	12	3
Thomas et al[20], 2015	10	3 episodes	168 vs 221 µmol/L at 2 mo (P = NS)	NA	NA
Bureau et al[16], 20171	27	After day 7: G1 vs G2: 17 vs 11 episodes; P = NS	G1 vs G2, at 3 mo: Increase of 18.1 vs 8.1 µmol/L (P = NS)	NA	NA
Stirnimann et al[18], 2017	56	NA	Increase of 46 µmol/L at 3 mo (P = NA)	5	1
Solà et al, 2017	10	18 episodes, 14 after day 7 in 7 patients	96 vs 105 µmol/L at 12 mo (P = NS)	3	8
Solbach et al[17], 2018	21	0	140 vs 168 µmol/L at 3 mo (P = NS)	11	4
Wong et al[20], 2020	30	11 episodes after day 7 in 9 patients	93 vs 107 µmol/L at 12 mo (P = NA)	1	3

¹In this randomized controlled study, G1 and G2 correspond to alfapump^® and iterative paracentesis groups, respectively. AKI: Acute kidney injury; NA: Not available; NS: Not significant.