Hepatocellular carcinoma and microbiota: Implications for clinical management and treatment

doi:10.4254/wjh.v14.i7.1319

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 27, 2022; 14(7): 1319-1332
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1319

Table 2 Correlation studies between intestinal microbial composition and response to immune checkpoint inhibitors

	Treatment	Responder	Non responder
Zheng et al[42]	Anti-PD1	↑ Akkermansia muciniphila; ↑ Ruminococcaceae	↑Proteobacteria
Li et al[9]	Anti-PD1	↑ Faecalibacterium	↑ Bacteroidales
Chung et al[43]	Anti-PD1	Dialister pneumosintes; Escherichia coli; Lactobacillus reteri; Streptococcus mutans; Enterococcus faecium; Streptococcus gordonii; Veillonella atypica; Granulicatella sp.; Trchuris trichiura; ↑ Firmicutes/Bacteroidetes ratio; ↓ Prevotella/Bacteroides ratio	Citrobacter freundii; Azospirillum sp.Enterococcus durans; ↑ Akkermansia species

↑: Increased; ↓: Decreased.

Citation: Spanu D, Pretta A, Lai E, Persano M, Donisi C, Mariani S, Dubois M, Migliari M, Saba G, Ziranu P, Pusceddu V, Puzzoni M, Astara G, Scartozzi M. Hepatocellular carcinoma and microbiota: Implications for clinical management and treatment. World J Hepatol 2022; 14(7): 1319-1332
URL: https://www.wjgnet.com/1948-5182/full/v14/i7/1319.htm
DOI: https://dx.doi.org/10.4254/wjh.v14.i7.1319