Hepatocellular carcinoma and microbiota: Implications for clinical management and treatment

doi:10.4254/wjh.v14.i7.1319

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Jul 27, 2022; 14(7): 1319-1332
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1319

Table 1 Human studies involving gut microbial composition in various hepatocellular carcinoma-related etiologies

		Microbiota balance
Ponziani et al[38]	Cirrhosis + HCC	↑ Bacteroides; ↑ Ruminococcus; ↑ Enterobacteriaceae	↓ Bifidobacterium; ↓ Akkermansia
Ren et al[41]	HBV cirrhosis + HCC	↑ Actinobacteria	↓ Verrucomicrobia
Liu et al[97]	NBNC cirrhosis + HCC	↑ Escherichia; ↑ Enterococcus	↓ Faecalibacterium;↓ Ruminococcus;↓ Ruminoclostridium
Huang et al[39]	HBV cirrhosis + HCC	↑ Bacteroides; ↑ Lachnospiracea incertae sedis; ↑ Clostridium XIVa

↑: Increased; ↓: Decreased; NBNC: Non-hepatitis B virus non- hepatitis C virus; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma.

Citation: Spanu D, Pretta A, Lai E, Persano M, Donisi C, Mariani S, Dubois M, Migliari M, Saba G, Ziranu P, Pusceddu V, Puzzoni M, Astara G, Scartozzi M. Hepatocellular carcinoma and microbiota: Implications for clinical management and treatment. World J Hepatol 2022; 14(7): 1319-1332
URL: https://www.wjgnet.com/1948-5182/full/v14/i7/1319.htm
DOI: https://dx.doi.org/10.4254/wjh.v14.i7.1319