Gut dysbiosis and body composition in cirrhosis

Table 2 Comparison of the main characteristics, body composition, and the abundance of major taxa of the gut microbiome between patients with cirrhosis and healthy persons

	Patients with cirrhosis (n = 46)	Healthy persons (n = 14)	P
Age, yr	55 [43-61]	51 [41-63]	0.484
Male/Female	18/28	3/11	0.187
Body mass index, kg/m2	27.0 [23.6-30.1]	21.1 [19.7-26.0]	0.002
Fat mass, %	34.7 [28.1-43.5]	24.5 [20.7-31.2]	0.002
Free-fat mass, %	65.3 [56.5-71.9]	75.5 [68.8-79.3]	0.002
Body cell mass, %	32.4 [28.0-36.5]	44.5 [38.4-46.0]	< 0.001
(Body cell mass)/(free-fat mass)	0.50 [0.46-0.55]	0.58 [0.55-0.60]	< 0.001
Extracellular fluid, %	20.1 [17.4-21.4]	18.6 [16.8-19.3]	0.044
Total fluid, %	47.9 [42.0-53.3]	51.7 [46.8-52.9]	0.238
(Extracellular fluid)/(total fluid)	0.41 [0.40-0.43]	0.36 [0.36-0.37]	< 0.001
Phase angle, °	5.3 [4.9-6.3]	7.0 [6.2-7.3]	< 0.001
Firmicutes	38.6 [27.7-52.9]	90.8 [85.7-94.1]	< 0.001
Bacteroidetes	38.6 [26.6-58.5]	5.9 [4.7-8.1]	< 0.001
Proteobacteria	5.5 [2.3-10.6]	0.4 [0.1-0.5]	< 0.001
Clostridia	36.2 [24.8-50.0]	89.3 [86.7-91.0]	< 0.001
Bacilli	0.4 [0.2-1.1]	0.1 [0.0-0.2]	< 0.001