Direct-acting antivirals for hepatitis C virus-infected patients with hepatocellular carcinoma

Table 1 Characteristics of patients

	Overall	With HCC	Without HCC	P value1
Case	311	53	258
Age in yr	68.1 ± 13.5	75.8 ± 6.7	66.5 ± 14.1	< 0.01
Male/Female	143/168	27/26	116/142	0.45
Diabetes, yes/no	47/264	19/34	28/230	< 0.01
Habitual alcohol use2, yes/no	56/255	12/41	44/214	0.33
Liver cirrhosis, yes/no	224/87	18/35	52/206	< 0.01
Genotype, 1b/2a, 2b/others	229/73/10	45/7/1	183/66/9	0.04
Alb in g/dL	3.9 ± 0.4	3.5 ± 0.4	4.0 ± 0.4	< 0.01
ALT in U/L	44.3 ± 45.0	40.3 ± 22.0	45.1 ± 48.3	0.48
Plt as × 104/μL	16.0 ± 5.9	12.9 ± 5.6	16.7 ± 5.8	< 0.01
Fib-4 index	3.87 ± 3.24	6.27 ± 4.64	3.37 ± 2.60	< 0.01
AFP in ng/mL	12.0 ± 35.2	23.7 ± 52.4	9.4 ± 29.6	0.047

¹Statistical significance set up as P < 0.05 as compared between with HCC vs without HCC.

²Habitual alcohol use is defined as daily alcohol consumption of > 20 g a woman or > 30 g for a man.

Alb: Albumin; AFP: Alpha fetoprotein; ALT: Alanine aminotransferase; Fib-4: Fibrosis-4; HCC: Hepatocellular carcinoma; Plt: Platelet.