Functions of three ubiquitin-conjugating enzyme 2 genes in hepatocellular carcinoma diagnosis and prognosis

Figure 4 The genetic alteration occurred in UBE2C, UBE2T, and UBE2S in liver cancer (1238 samples from the Cancer Genome Atlas). A: Genetic alteration occurred in UBE2C, UBE2T, and UBE2S in HCC; B: UBE2T and UBE2S, overall alteration frequency 6.23% (23/369 cases) in hepatocellular carcinoma including 22 cases implication and 1 case of mutation. In hepatobiliary cancer type, the alteration frequency is 0.28 (2/712) with 1 case of amplification and 1 case of mutation; C: UBE2T genetic alteration frequency 5.69% (21/369 cases) categorized by cancer type; D: UBE2S genetic alteration frequency 0.54% (2/369 cases) in HCC (1 case amplification and 1 case mutation); In hepatobiliary cancer, UBE2S alteration frequency is 0.28% (2/712 cases) (1 case amplification and 1 case mutation).