Total cholesterol to high-density lipoprotein ratio and nonalcoholic fatty liver disease in a population with chronic hepatitis B

Table 2 Binary logistic regression of independent risk factors of nonalcoholic fatty liver disease

Parameters	Statistics	OR	(95%CI)	P value
Gender (male)	129 (70.5%)	2.02	(0.78-5.23)	0.15
Age	45.41 ± 11.59	0.96	(0.92-1.00)	0.03
BMI	23.14 ± 2.63	1.40	(1.20-1.63)	< 0.01
AST	25 (21–32)	0.99	(0.98-1.02)	0.99
ALT	28 (19–41)	1.01	(1.00-1.02)	0.04
γ-GT	25 (19–37)	1.02	(1.01-1.04)	< 0.01
PLT	208.37 ± 61.13	1.01	(1.00-1.01)	0.03
HBsAg (IU/mL)				0.09
≤ 1500	105 (57.4%)	0.51	(0.24-1.11)
> 1500	78 (42.6%)	1.95	(0.90-4.22)
CRE	77.73 ± 17.96	1.01	(0.99-1.03)	0.34
UA	345.20 ± 92.53	1.01	(1.00-1.01)	< 0.01
TG	1.22 ± 0.63	6.72	(3.07-14.71)	< 0.01
TC	4.59 ± 0.98	1.46	(1.00-2.15)	0.05
HDL-C	1.18 ± 0.25	0.19	(0.03-1.16)	0.07
LDL-C	2.72 ± 0.68	1.94	(1.11-3.39)	0.02
ApoA1	1.36 ± 0.19	0.81	(0.10-6.44)	0.84
ApoB	0.91 ± 0.18	11.86	(1.37-102.86)	0.03
TC/HDL-C	3.94 ± 0.79	2.55	(1.55-4.19)	< 0.01
HBV-DNA (+)	131 (71.6%)	3.74	(1.70-8.28)	< 0.01
HBeAg (+)	49 (26.8%)	1.31	(0.57-2.00)	0.53
NAs	168 (91.8%)	0.15	(0.05-0.44)	< 0.01

TC/HDL-C: Cholesterol to high-density lipoprotein cholesterol; NAFLD: Non-alcoholic fatty liver disease; BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; γ-GT: γ-glutamyl transpeptidase; PLT: Platelets; HBsAg: Hepatitis B virus surface antigen; CRE: Creatinine; UA: Uric acid; TG: Triglyceride; TC: Total cholesterol; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; HBV-DNA(+): Hepatitis B virus DNA > 100 IU/mL; HBeAg(+): Hepatitis B e antigen positive; NAs: Nucleoside analogues.