Assessment of periportal fibrosis in Schistosomiasis mansoni patients by proton nuclear magnetic resonance-based metabonomics models

Table 1 Demographic and laboratorial characteristic of 41 patients with Schistosomiasis mansoni, Pernambuco, Brazil, 2020

Characteristic	Total	Mild PPF (C pattern)	Significant PPF (D/E/F pattern)	P value
n	41	10	31	-
Age (yr)	57 (18-80)	48.1 (18-75)	57.2 (25-80)	0.0865a
Sex				0.4820b
Male	17 (41%)	5 (40%)	12 (39%)
Female	24 (59%)	5 (50%)	19 (61%)
AST (U/L)	29.0 ± 2.6	24.3 ± 1.9	30.0 ± 2.9	0.3328c
ALT (U/L)	29.0 ± 2.2	26.2 ± 4.5	30.0 ± 3.2	0.4584c
ALP (U/L)	262 ± 33	329 ± 113	238 ± 22	0.6379c
GGT (/LSN)	62 ± 12	35 ± 16	71.2 ± 14.0	0.0013c
Platelets count (/mm3)	131 ± 12	218 ± 15	102 ± 11	0.0001c
Total Cholesterol (mg/dL)	169.0 ± 4.6	174.0 ± 7.2	167.8 ± 5.6	0.4626c
HDL (mg/dL)	45.7 ± 2.0	49 ± 5.7	44.6 ± 2.0	0.4863c
LDL (mg/dL)	105.0 ± 3.8	108 ± 4.7	104 ± 4.8	0.3760c
Glucose (mg/dL)	93.6 ± 5.2	97 ± 14	92 ± 5.1	0.9451c

^aUnpaired t test.

^bFisher’s exact test.

^cMann-Whitney test.

Data presented as Mean values ± standard deviation. ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase; HDL: High-density lipoprotein cholesterol; LDL: Low-density lipoprotein cholesterol; PPF: Periportal fibrosis.