Review on hepatitis B virus precore/core promoter mutations and their correlation with genotypes and liver disease severity

Table 1 Qualitative and quantitative factors and the level of each factor associated with hepatitis B virus-related hepatocellular carcinoma

Patient group	Qualitative factors	Quantitative factors
Low risk	Genotype A/B	Low level of HBV-DNA in serum; low level of HBsAg in serum
High risk	Genotype C/D; BCP mutation (A1762T/G1764A); pre-S deletion	High level of HBV-DNA in serum; high level of HBsAg in serum

HBV: Hepatitis B virus; BCP: Basal core promoter; HBsAg: Hepatitis B surface antigen.